Restrictive transfusion on clinical outcomes in ICU patients
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摘要: 目的: 探讨限制性输血对ICU患者临床转归的影响。方法: 选择接受红细胞输血治疗的271例ICU患者作为研究对象。根据不同输血策略将患者分为开放性输血组(输血前Hb<100 g/L)与限制性输血组(输血前Hb<70 g/L)。收集2组患者的年龄、性别、疾病分布等一般资料;对2组患者进行急性生理与慢性健康状况评分Ⅱ(APACHEⅡ评分)和多器官功能障碍评分(MODS);记录2组ICU内输血情况及Hb变化情况;观察2组患者 3周内病死率、住院期间病死率,以及重症感染、肺水肿、心力衰竭发生率等。结果: ①2组在平均年龄、APACHEⅡ评分、疾病分布等方面无明显差异(P>0.05);②限制性输血组住院期间每例平均输注红细胞(4.5±3.7) U,低于开放性输血组的(6.8±4.6)U,差异有统计学意义(P<0.05)。限制性输血组入院时Hb、ICU内输红细胞前后Hb、出院时Hb均低于开放性输血组(P<0.05);③限制性输血组3周内病死率与住院期间病死率低于开放性输血组,但差异无统计学差异(P>0.05),限制性输血组重症感染、肺水肿、心力衰竭的发生率及MODS 评分、≥ 3个器官衰竭等方面明显低于开放性输血组(P<0.05)。结论: 对ICU患者实施限制性输血策略减少临床不必要的输血,节约宝贵的血液资源,降低输血并发症的发生率。
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Key words:
- restrictive transfusion /
- ICU patients /
- clinical outcome
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