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摘要: 目的:提高对粒细胞肉瘤(GS)的临床病理特征、诊断及治疗的认识。方法:对4例GS患者的临床表现、诊断及治疗进行分析,并复习相关文献。结果:非白血性GS 1 例,白血性GS 3例,均来源于急性髓系白血病,其中2例患者已死亡,生存时间分别为12个月和7个月。结论:GS诊断和鉴别诊断主要依靠病理形态学及免疫组织化学。原发性GS预后差,早期确诊和早期采用急性髓系白血病方案全身化疗对控制疾病进展有一定的疗效。Abstract: Objective: To explore the clinical pathologic feature,diagnosis and therapy of granulocytic sarcoma (GS).Method: Clinical data of four cases of GS were reported and the related-literatures were reviewed.Result: One case was non-leukemic GS and the other 3 cases were leukemic GS,which originated from acute myeloid leukemia.Two of the leukemic GS patients had died and the survival time was 12 months and 7 months,respectively.Conclusion: The diagnosis and differential diagnosis of GS mainly depend on pathomorphology and immunohistochemistry.The prognosis of primary GS is poor.Early diagnosis and early application of systemic chemotherapy for acute myeloid leukemia may have a certain effect on controlling disease progression.
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Key words:
- granulocytic sarcoma /
- clinical features
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