3 486例血液病住院患者并发血栓栓塞的临床研究

张文曦; 孔祥图; 代兴斌; 于慧; 张冰

doi:10.13201/j.issn.1004-2806.2018.01.006

3 486例血液病住院患者并发血栓栓塞的临床研究

- 南京中医药大学附属医院血液科(南京, 210029)
基金项目:
江苏省中医药局科技项目(No:FY201501)

江苏省六大人才高峰项目资助(No:2015-WSN-055)

第二批江苏省名老中医药专家传承工作室建设项目[苏中医科教(2016)6号]

江苏高校优势学科建设工程[苏政办发(2014)37号]

第四批全国中医优秀人才研修项目[国中医药人教发(2017)24号]

详细信息

通讯作者: 孔祥图,E-mail:kongxiangtu@qq.com

中图分类号: R733

收稿日期: 2017-10-16

The clinical study of thrombosis in 3 486 in-patients with hematologic diseases

- Department of Hematology, the First Affiliated Hospital of Nanjing University of Traditional China Medicine, Nanjing, 210029, China

More Information

Corresponding author: KONG Xiangtu, E-mail: kongxiangtu@qq.com

Received Date: 16 October 2017

摘要

摘要: 目的:观察血液病患者并发血栓情况,分析高危因素,为今后临床预防、治疗血栓栓塞提供依据和指导。方法:回顾性分析血液科住院患者3486例,记录其中发生血栓的患者情况,并加以统计。结果:总体血栓发生率为1.49%,恶性血液病发生率2.07%,占全部血栓的86.54%;非恶性血液病发生率0.53%,占全部血栓的13.46%,二者比较差异有统计学意义(P<0.001)。高龄、深静脉置管、输血、糖皮质激素、化疗、血小板计数减少为血栓栓塞的高危因素(P<0.05)。结论:恶性血液病并发血栓栓塞的风险明显高于非恶性血液病,血液病患者血小板计数减少血栓风险更高。
- 血栓 /
- 恶性血液病 /
- 血小板计数
Abstract: Objective:To study the incidence of thrombosis in hematologic patients and analyze the risk factors of thrombosis,in order to provide evidence and guidance for prevention and treatment of thrombosis.Method:A total of 3486 in-patients with hematologic diseases were enrolled.We recorded and analyzed clinical biological characteristics and related risk factors of concomitant thrombosis.Result:The overall incidence of thrombosis was 1.49%.The incidence of malignant hematologic diseases was 2.07%,which accounted for 86.54% of the total thrombosis.The non-malignant hematologic diseases was 0.53%,which accounted for 13.46% of the total thrombosis.There were significant differences between two groups (P<0.001).Advanced age,deep vein catheterization,blood transfusion,glucocorticoids,chemotherapy and decreased platelet count were high risk factors for thrombosis (P<0.05).Conclusion:The risk of thrombosis in malignant hematologic diseases is significantly higher than that of non-malignant hematologic diseases.Thrombocytopenia is associated with higher risk of thrombosis in patients with hematologic diseases.
- thrombosis /
- malignant hematologic diseases /
- platelet count

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