病理性假性缺氧在骨髓增生异常综合征发病机制中的研究

张悦, 肖志坚. 病理性假性缺氧在骨髓增生异常综合征发病机制中的研究[J]. 临床血液学杂志, 2019, 32(11): 821-825. doi: 10.13201/j.issn.1004-2806.2019.11.001
引用本文: 张悦, 肖志坚. 病理性假性缺氧在骨髓增生异常综合征发病机制中的研究[J]. 临床血液学杂志, 2019, 32(11): 821-825. doi: 10.13201/j.issn.1004-2806.2019.11.001
ZHANG Yue, XIAO Zhijian. Comments on “Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes”[J]. J Clin Hematol, 2019, 32(11): 821-825. doi: 10.13201/j.issn.1004-2806.2019.11.001
Citation: ZHANG Yue, XIAO Zhijian. Comments on “Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes”[J]. J Clin Hematol, 2019, 32(11): 821-825. doi: 10.13201/j.issn.1004-2806.2019.11.001

病理性假性缺氧在骨髓增生异常综合征发病机制中的研究

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    通讯作者: 肖志坚,E-mail:zjxiao@hotmail.com
  • 中图分类号: R733

Comments on “Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes”

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  • [1]

    Corey SJ,Minden MD,Barber DL,et al.Myelodysplastic syndromes:the complexity of stem-cell diseases[J].Nat Rev Cancer,2007,7:118-129.

    [2]

    Tefferi A,Vardiman JW.Myelodysplastic syndromes[J].N Engl J Med,2009,361:1872-1885.

    [3]

    Zhou T,Kinney MC,Scott LM,et al.Revisiting the case fo genetically engineered mouse models in human myelodysplastic syndrome research[J].Blood,2015,126:1057-1068.

    [4]

    Nimer SD.Myelodysplastic syndromes[J].Blood,2008,111:4841-4851.

    [5]

    Raza A,Galili N.The genetic basis of phenotypic heterogeneity in myelodysplastic syndromes[J].Nat Rev Cancer,2012,12:849-859.

    [6]

    Semenza GL.Targeting HIF-1 for cancer therapy[J].Nat Rev Cancer,2003,3:721-732.

    [7]

    Takubo K,Goda N,Yamada W,et al.Regulation of the HIF-1alpha level is essential for hematopoietic stem cells[J].Cell Stem Cell,2010,7:391-402.

    [8]

    Palazon A,Goldrath AW,Nizet V,et al.HIF transcription factors,inflammation,and immunity[J].Immunity,2014,41:518-528.

    [9]

    Ganan-Gomez I,Wei Y,Starczynowski DT,et al.Deregulation of innate immune and inflammatory signaling in myelodysplastic syndromes[J].Leukemia,2015,29:1458-1469.

    [10]

    Chasis JA,Mohandas N.Erythroblastic islands:niches for erythropoiesis[J].Blood,2008,112:470-478.

    [11]

    Zhang Y,Yan X,Sashida G,et al.Stress hematopoiesis reveals abnormal control of self-renewal,lineage bias,and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells[J].Blood,2012,120:1118-1129.

    [12]

    Zhang Y,Chen A,Yan XM,et al.Disordered epigenetic regulation in MLL-related leukemia[J].Int J Hematol,2012,96:428-437.

    [13]

    Maxwell PH,Wiesener MS,Chang GW,et al.The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis[J].Nature,1999,399:271-275.

    [14]

    Ravi R,Mookerjee B,Bhujwalla ZM,et al.Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha[J].Genes Dev,2000,14:34-44.

    [15]

    van Nederveen FH,Korpershoek E,Lenders JW,et al.Somatic SDHB mutation in an extraadrenal pheochromocytoma[J].N Engl J Med,2007,357:306-308.

    [16]

    Jafri M,Wake NC,Ascher DB,et al.Germline mutations in the CDKN2B tumor suppressor gene predispose to renal cell carcinoma[J].Cancer Discov,2015,5:723-729.

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出版历程
收稿日期:  2019-08-27

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