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Abstract: KX antigen is one of the two "phosphorylated palmitate alcoholated proteins" on the membrane. It is a Ⅲ transmembrane protein. It is linked to the Kell antigen glycoprotein on the membrane and is related to the Kell glycoprotein penetration through the membrane. The phenotype of red blood cells lacking KX antigen is the Mcleod phenotype. This phenotype is clinically expressed as Mcleod syndrome which is a genetic disease. Anti-KX antibodies can cause transfusion hemolysis.
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Key words:
- KX antigen /
- Mcleod syndrome /
- Kell antigen /
- endokinin-3 hydrolase /
- transfusion hemolysis
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