《多发性骨髓瘤相关静脉血栓栓塞症防治中国专家共识(2022年版)》解读

唐亮, 胡豫. 《多发性骨髓瘤相关静脉血栓栓塞症防治中国专家共识(2022年版)》解读[J]. 临床血液学杂志, 2023, 36(7): 457-460. doi: 10.13201/j.issn.1004-2806.2023.07.001
引用本文: 唐亮, 胡豫. 《多发性骨髓瘤相关静脉血栓栓塞症防治中国专家共识(2022年版)》解读[J]. 临床血液学杂志, 2023, 36(7): 457-460. doi: 10.13201/j.issn.1004-2806.2023.07.001
TANG Liang, HU Yu. Interpretation of expert consensus on the prevention and treatment of multiple myeloma related venous thromboembolism in China(2022)[J]. J Clin Hematol, 2023, 36(7): 457-460. doi: 10.13201/j.issn.1004-2806.2023.07.001
Citation: TANG Liang, HU Yu. Interpretation of expert consensus on the prevention and treatment of multiple myeloma related venous thromboembolism in China(2022)[J]. J Clin Hematol, 2023, 36(7): 457-460. doi: 10.13201/j.issn.1004-2806.2023.07.001

《多发性骨髓瘤相关静脉血栓栓塞症防治中国专家共识(2022年版)》解读

详细信息
    作者简介:

    胡豫,医学博士、教授、主任医师、博士生导师,华中科技大学同济医学院附属协和医院院长,教育部生物靶向治疗重点实验室主任,华中科技大学血液病学研究所所长。国家杰出青年科学基金获得者、国家科技进步二等奖获得者、全国创新争先奖章获得者、“长江学者”特聘教授、全国教书育人楷模获得者、全国优秀医院院长获得者、何梁何利基金奖获得者。担任中华医学会血液学分会候任主委、中华医学会内科学分会副主委、中国医师协会血液科医师分会副会长、中国医院协会副会长、中国病理生理学会实验血液学会副主委、国际血栓与止血学会教育委员会委员、湖北省医学会血液病分会主委。担任本专业国际刊物Thrombosis ResearchThrombosis and Haemostasis副主编,《临床内科杂志》《临床急诊杂志》主编、《中华血液学杂志》《临床血液学杂志》《中国医院管理》副主编、《中华医院管理杂志》编委等。从事血液病医疗工作30余年,主持临床一线工作。在各种疑难血液病的临床诊治方面具有丰富经验,特别是对出凝血疾病如难治免疫性血小板减少症、易栓症,恶性血液疾病如多发性骨髓瘤等具有较深造诣

    通讯作者: 胡豫,E-mail:dr_huyu@126.com
  • 中图分类号: R733.3

Interpretation of expert consensus on the prevention and treatment of multiple myeloma related venous thromboembolism in China(2022)

More Information
  • 多发性骨髓瘤(MM)是一种浆细胞克隆性增殖的恶性疾病。静脉血栓栓塞症(VTE)是MM常见的并发症之一,关键在于预防、早期诊断和治疗,但我国一直以来缺乏更进一步规范MM相关VTE防治的共识。结合国内外研究和指南,中华医学会血液学分会浆细胞疾病学组和血栓与止血学组共同制定了《多发性骨髓瘤相关静脉血栓栓塞症防治中国专家共识(2022年版)》。为更好地指导临床实践,文章拟对该共识的诊断部分、风险评估部分、分层预防部分(包括肾功能不全和血小板减少患者)和治疗部分进行解读。
  • 加载中
  • [1]

    中华医学会血液学分会浆细胞疾病学组, 中华医学会血液学分会血栓与止血学组. 多发性骨髓瘤相关静脉血栓栓塞症防治中国专家共识(2022年版)[J]. 中华血液学杂志, 2022, 43(9): 726-731.

    [2]

    Geersing GJ, Zuithoff NP, Kearon C, et al. Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis[J]. BMJ, 2014, 348: g1340. doi: 10.1136/bmj.g1340

    [3]

    Geersing GJ, Erkens PM, Lucassen WA, et al. Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study[J]. BMJ, 2012, 345: e6564. doi: 10.1136/bmj.e6564

    [4]

    Mehta J, Singhal S. Hyperviscosity syndrome in plasma cell dyscrasias[J]. Semin Thromb Hemost, 2003, 29(5): 467-471. doi: 10.1055/s-2003-44554

    [5]

    Horváth-Puhó E, Suttorp MM, Frederiksen H, et al. Erythropoiesis-stimulating agents and cardiovascular events in patients with myelodysplastic syndrome and multiple myeloma[J]. Clin Epidemiol, 2018, 10: 1371-1380. doi: 10.2147/CLEP.S172306

    [6]

    Li A, Wu Q, Luo SH, et al. Derivation and validation of a risk assessment model for immunomodulatory drug-associated thrombosis among patients with multiple myeloma[J]. J Natl Compr Canc Netw, 2019, 17(7): 840-847. doi: 10.6004/jnccn.2018.7273

    [7]

    Sanfilippo KM, Luo SH, Wang TF, et al. Predicting venous thromboembolism in multiple myeloma: development and validation of the IMPEDE VTE score[J]. Am J Hematol, 2019, 94(11): 1176-1184. doi: 10.1002/ajh.25603

    [8]

    Swan D, Rocci A, Bradbury C, et al. Venous thromboembolism in multiple myeloma-choice of prophylaxis, role of direct oral anticoagulants and special considerations[J]. Br J Haematol, 2018, 183(4): 538-556. doi: 10.1111/bjh.15684

    [9]

    Baker RI, Coughlin PB, Gallus AS, et al. Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis[J]. Med J Aust, 2004, 181(9): 492-497. doi: 10.5694/j.1326-5377.2004.tb06407.x

    [10]

    Fotiou D, Gavriatopoulou M, Terpos E. Multiple myeloma and thrombosis: prophylaxis and risk prediction tools[J]. Cancers(Basel), 2020, 12(1): 191.

    [11]

    Wiggins BS, Dixon DL, Neyens RR, et al. Select drug-drug interactions with direct oral anticoagulants: JACC review topic of the week[J]. J Am Coll Cardiol, 2020, 75(11): 1341-1350.

    [12]

    Streiff MB, Holmstrom B, Angelini D, et al. NCCN guidelines insights: cancer-associated venous thromboembolic disease, version 2.2018[J]. J Natl Compr Canc Netw, 2018, 16(11): 1289-1303. doi: 10.6004/jnccn.2018.0084

    [13]

    Dimopoulos MA, Kastritis E, Rosinol L, et al. Pathogenesis and treatment of renal failure in multiple myeloma[J]. Leukemia, 2008, 22(8): 1485-1493. doi: 10.1038/leu.2008.131

    [14]

    Fored CM, Ejerblad E, Lindblad P, et al. Acetaminophen, aspirin, and chronic renal failure[J]. N Engl J Med, 2001, 345(25): 1801-1808. doi: 10.1056/NEJMoa010323

    [15]

    Farge D, Bounameaux H, Brenner B, et al. International clinical practice guidelines including guidance for direct oral anticoagulants in the treatment and prophylaxis of venous thromboembolism in patients with cancer[J]. Lancet Oncol, 2016, 17(10): e452-e466. doi: 10.1016/S1470-2045(16)30369-2

    [16]

    Susen S, Tacquard CA, Godon A, et al. Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring[J]. Crit Care, 2020, 24(1): 364. doi: 10.1186/s13054-020-03000-7

    [17]

    Derebail VK, Rheault MN, Kerlin BA. Role of direct oral anticoagulants in patients with kidney disease[J]. Kidney Int, 2020, 97(4): 664-675. doi: 10.1016/j.kint.2019.11.027

    [18]

    Lonial S, Waller EK, Richardson PG, et al. Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma[J]. Blood, 2005, 106(12): 3777-3784. doi: 10.1182/blood-2005-03-1173

  • 加载中
计量
  • 文章访问数:  776
  • PDF下载数:  408
  • 施引文献:  0
出版历程
收稿日期:  2023-05-29
刊出日期:  2023-07-01

目录