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摘要: 免疫性血小板减少症是临床上最常见的出血性疾病之一,部分患者因合并症有手术治疗的需要。为减少不良反应发生、保障患者安全,本文通过归纳总结国内外指南共识、临床研究及病例报道,分别针对免疫性血小板减少症患者围手术期的术前评估、治疗及术后管理进行介绍,并提出相应的建议。Abstract: Immune thrombocytopenia(ITP) is a common clinical disorder with a variably increased risk of bleeding. Some ITP patients have complications and need surgery. From summarizing related guidelines, consensus, clinical trials and case reports, we make recommendation on preoperative assessment, perioperative treatment and postoperative management for ITP patients, aimed at minimizing adverse events and ensure safety.
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Key words:
- immune thrombocytopenia /
- perioperative period /
- evaluation /
- treatment
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表 1 成人ITP出血评分系统
分值 年龄/岁 皮下出血(瘀点/瘀斑/血肿) 黏膜出血(鼻腔/齿龈/口腔血疱/结膜) 深部器官出血 ≥65 ≥75 头面部 其他部位 偶发、可自止 多发、难止 伴贫血 内脏(肺、胃肠道、泌尿生殖系统) 中枢神经系统 无贫血 伴贫血 危及生命 1 √ √ 2 √ √ √ 3 √ √ 5 √ √ 8 √ √ -
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