产科弥散性血管内凝血诊断与治疗专家共识解读

王雅丹; 胡豫

doi:10.13201/j.issn.1004-2806.2024.07.004

产科弥散性血管内凝血诊断与治疗专家共识解读

王雅丹¹,
胡豫^1, ,

- 华中科技大学同济医学院附属协和医院血液病研究所(武汉，430022)

详细信息

作者简介:
胡豫，医学博士、教授、主任医师、博士生导师，华中科技大学同济医学院附属协和医院院长，教育部生物靶向治疗重点实验室主任，华中科技大学血液病学研究所所长。国家杰出青年科学基金获得者、国家科技进步二等奖获得者、全国创新争先奖章获得者、“长江学者”特聘教授、全国教书育人楷模获得者、全国优秀医院院长获得者、何梁何利基金奖获得者、中国医院管理突出贡献奖获得者。担任中华医学会血液学分会候任主委、中华医学会内科学分会副主委、中国医师协会血液科医师分会副会长、中国医院协会副会长、中国病理生理学会实验血液学会副主委、国际血栓与止血学会教育委员会委员。担任本专业国际刊物Thrombosis Research、Thrombosis and Haemostasis副主编，《临床内科杂志》《临床血液学杂志》《临床急诊杂志》主编、《中华血液学杂志》《中国医院管理》副主编、《中华医院管理杂志》编委等。从事血液病医疗工作30余年，主持临床一线工作。在各种疑难血液病的临床诊治方面具有丰富经验，特别是对出凝血疾病如难治免疫性血小板减少症、易栓症，恶性血液疾病如多发性骨髓瘤等方面具有较深造诣

通讯作者: 胡豫，E-mail：dr_huyu@126.com

中图分类号: R554.8

收稿日期: 2024-04-09

刊出日期: 2024-07-01

Interpretation of expert consensus on diagnosis and treatment of disseminated intravascular coagulation in obstetrics

WANG Yadan¹,
HU Yu^1, ,

- Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

More Information

Corresponding author: HU Yu, E-mail: dr_huyu@126.com

Received Date: 09 April 2024

Publish Date: 01 July 2024

摘要

摘要: 弥散性血管内凝血(disseminated intravascular coagulation，DIC)是一种严重的临床综合征，由于多种疾病导致微血管体系损伤，诱导凝血酶过度活化，广泛形成微血管血栓、大量凝血因子消耗，继而发生纤溶亢进。在妊娠期，胎盘早剥、子痫前期/HELLP综合征、羊水栓塞、严重感染等均为诱发DIC的严重产科并发症。其临床起病急、变化快，易发展为严重休克和多器官功能衰竭，严重威胁母婴的健康和生命。为了提高我国临床工作者对该疾病的认识，降低孕产妇和胎婴儿的死亡率，改善妊娠结局，中华医学会血液学分会起草了《产科弥散性血管内凝血临床诊断与治疗中国专家共识》。文章就该共识中有关产科DIC的发病机制、临床表现、实验室检查、诊断标准和治疗等方面进行了详细解读。
- 弥散性血管内凝血 /
- 产科 /
- 诊断 /
- 治疗
Abstract: Disseminated intravascular coagulation(DIC) is an acquired syndrome characterized by the intravascular activation of coagulation with a loss of localization arising from different causes. It can originate from and cause damage to the microvasculature, which if sufficiently severe, can produce organ dysfunction. On the basis of physiologic hypercoagulability in pregnant women, it is easy to induce DIC if placental abruption, preeclampsia, HELLP syndrome, amniotic fluid embolism, infection and other serious conditions are complicated. The clinical manifestations show the characteristics of rapid onset and rapid change, and are prone to severe shock and multiple organ failure, which seriously affect the survival and health of mothers and infants. To improve the awareness of Chinese clinical workers about this disease, reduce maternal and fetal mortality, and improve pregnancy outcomes, the Hematology branch of the Chinese Medical Association formulated the "Chinese Expert Consensus on Clinical Diagnosis and Treatment of Obstetric Disseminated Intravascular Coagulation". This article interprets the pathogenesis, clinical manifestations, laboratory tests, diagnostic criteria and treatment of obstetric DIC in the consensus.
- disseminated intravascular coagulation /
- obstetrics /
- diagnosis /
- treatment

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