Survey of irregular red blood cell antibody in Nanyang city
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摘要: 目的：了解南阳市患者手术前备血及受血者红细胞血型不规则抗体的发生频率及特异性抗体的分布特点。方法：选取16 900例患者用卡式微柱凝胶法进行红细胞血型不规则抗体筛查，对检出抗体阳性者鉴定其特异性及免疫球蛋白类型。结果：检出红细胞血型不规则抗体147例（0.87%），其中男29例（0.52%），女118例（1.04%）。1 673例孕妇检出红细胞血型不规则抗体30例（1.80%）。IgM类抗体77例、IgG类抗体32例、IgM加IgG类抗体12例，37℃反应阳性者26例。检出较多的特异性抗体依次为抗-M、Rh系统抗体、抗-Le、抗-P1和抗-JK等。结论：南阳市患者红细胞血型不规则抗体发生频率和分布特点与其他地区不同，检出率较高，提示对于拟输血者特别是孕妇应例行红细胞血型不规则抗体检测。Abstract: Objective: To study the incidence and the distribution characteristics of iregular antibodies of red blood cell group in patients of Nanyang region,Henan provinces.Method: 16900 patients (male 5552 and female 11348) were detected erythrocyte irregular antibodies by Microcolum gel Coombs test. The positive patients were further identified their antibody specificity and immunoglobulin type.Result: 147 positive cases (0.87%),including 29 male(0.52%)and 118 female(1.04%),were detected out.30 out of 1673 pregnant women(1.8%) were positive. There were 77 cases of IgM type,32 cases of IgG,12 cases of IgM +IgG,and 26 cases of 37℃.The incidence of the specificity type from high to low were anti-M, Rh, anti-Le, anti-P1 and anti-JK.Conclusion: The incidence of erythrocyte irregular antibodies and the specificity type in Nanyang region were different from other regions and countries. Our study supported that it should be a routine check of erythrocyte irregular antibodies for the patients who plan a blood transfusion, especially for pregnant women.
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Key words:
- blood group /
- red blood cells /
- irregular antibodies /
- microcolumn gel /
- coombs test
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