急性髓性细胞白血病的分子遗传学研究进展

王龙, 徐燕丽. 急性髓性细胞白血病的分子遗传学研究进展[J]. 临床血液学杂志, 2013, 26(7): 509-512.
引用本文: 王龙, 徐燕丽. 急性髓性细胞白血病的分子遗传学研究进展[J]. 临床血液学杂志, 2013, 26(7): 509-512.
WANG Long, XU Yanli. Advances in molecular genetics of acute myeloid leukemia[J]. J Clin Hematol, 2013, 26(7): 509-512.
Citation: WANG Long, XU Yanli. Advances in molecular genetics of acute myeloid leukemia[J]. J Clin Hematol, 2013, 26(7): 509-512.

急性髓性细胞白血病的分子遗传学研究进展

详细信息
    通讯作者: 徐燕丽,E-mail:xuyanli62@sohu.com
  • 中图分类号: R733.71

Advances in molecular genetics of acute myeloid leukemia

More Information
  • 加载中
  • [1]

    MROZEK K,MARCUCCI G,PASCHKA P,et al.Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics:are we ready for a prognostically prioritized molecular classification?[J].Blood,2007,109:431-448.

    [2]

    MCDEVITT M A.Clinical applications of epigenetic markers and epigenetic profiling in myeloid malignancies[J].Semin Oncol,2012,39:109-122.

    [3]

    HOU H A,KUO Y Y,LIU C Y,et al.DNMT3A mutations in acute myeloid leukemia:stability during disease evolution and clinical implications[J].Blood,2012,119:559-568.

    [4]

    LEY T J,DING L,WALTER M J,et al.DNMT3A mutations in acute myeloid leukemia[J].N Engl J Med,2010,363:2424-2433.

    [5]

    LAROCHELLE O,BERTOLI S,VERGEZ F,et al.Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin?[J].Oncotarget,2011,2:850-861.

    [6]

    PATEL J P,GONEN M,FIGUEROA M E,et al.Prognostic relevance of integrated genetic profiling in acute myeloid leukemia[J].N Engl J Med,2012,366:1079-1089.

    [7]

    米瑞华,吕晓东,魏旭东,等.急性髓系白血病患者IDH1和IDH2基因突变的检测及其临床意义[J].中华血液学杂志,2011,32(9):610-613.

    [8]

    SCHNITTGER S,HAFERLACH C,ULKE M,et al.IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status[J].Blood,2010,116:5486-5496.

    [9]

    THOL F,DAMM F,WAGNER K,et al.Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia[J].Blood,2010,116:614-616.

    [10]

    PASCHKA P,SCHLENK R F,GAIDZIK V I,et al.IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication[J].J Clin Oncol,2010,28:3636-3643.

    [11]

    ROCKOVA V,ABBAS S,WOUTERS B J,et al.Risk stratification of intermediate-risk acute myeloid leukemia:integrative analysis of a multitude of gene mutation and gene expression markers[J].Blood,2011,118:1069-1076.

    [12]

    BERMAN J N,GERBING R B,ALONZO T A,et al.Prevalence and clinical implications of NRAS mutations in childhood AML:a report from the Children's Oncology Group[J].Leukemia,2011,25:1039-1042.

    [13]

    PARK S H,CHI H S,MIN S K,et al.Prognostic impact of C-kit mutations in core binding factor acute myeloid leukemia[J].Leuk Res,2011,35:1376-1383.

    [14]

    张寒,郑胡镛.RUNX1表观遗传机制在白血病发生中的作用研究进展[J].中国实验血液学杂志,2010,18(2):525-530.

    [15]

    SILVA F P,SWAGEMAKERS S M,ERPELINCK-VERSCHUEREN C,et al.Gene expression profiling of minimally differentiated acute myeloid leukemia:M0 is a distinct entity subdivided by RUNX1 mutation status[J].Blood,2009,114:3001-3007.

    [16]

    TANG J L,HOU H A,CHEN C Y,et al.AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia:prognostic implication and interaction with other gene alterations[J].Blood,2009,114:5352-5361.

    [17]

    CARBUCCIA N,TROUPLIN V,GELSI-BOYER V,et al.Mutual exclusion of ASXL1 and NPM1 mutations in a series of acute myeloid leukemias[J].Leukemia,2010,24:469-473.

    [18]

    CHOU W C,HUANG H H,HOU H A,et al.Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1(ASXL1) mutations[J].Blood,2010,116:4086-4094.

    [19]

    BAKER L A,ALLIS C D,WANG G G.PHD fingers in human diseases:disorders arising from misinterpreting epigenetic marks[J].Mutat Res,2008,647(1-2):3-12.

    [20]

    VAN VLIERBERGHE P,PATEL J,ABDEL-WAHAB O,et al.PHF6 mutations in adult acute myeloid leukemia[J].Leukemia,2011,25:130-134.

  • 加载中
计量
  • 文章访问数:  26
  • PDF下载数:  229
  • 施引文献:  0
出版历程
收稿日期:  2012-06-16

目录