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Abstract: Genomics technology is widely applied in acute myeloid leukemia (AML) at present.A large number of abnormal genes associated with AML have been found in succession.However,there are 40% to 49% patients who were the normal karyotype (NK) in AML.For this reason,it is very important to supplement the molecular genetics studies to assess the prognosis of NK-AML patients.Therefore,new genes have the great significance in improving the prognosis of AML classification and guiding the diagnosis and treatment of NK-AML patients.
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Key words:
- acute myeloid leukemia /
- normal karyotype /
- prognosis /
- molecular genetics
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