Abstract: Objective:To understand the status of register, report,referral and follow-up of tuberculosis patients in Wuhan city, in order to provide basis for formulating tuberculosis controlling strategy. Method:Monthly report form and related data of China TB prevention and control reported by counties and districts from 2004 to 2010 were analyzed and checked. Result:57 319 TB patients had been actually reported from direct network report system of the comprehensive hospitals in Wuhan city from 2004 to 2010, 23 859 cases had visited the Institutes for TB Control and Prevention. The arrival rate of follow-up and the total arrival rate of TB patients in other hospitals and clinics had increased from 42.0 % and 71.4% in 2004 to 90.7% and 95.5 % in 2010. but the referral arrival rate had been around 40%,which had not been improved obviously. Conclusion:Wuhan had made progress obviously in the work of detecting tuberculosis patients and follow-up,but institutes for TB control and prevention and medical institutions must strengthen further in order to coordinate and supervise the work of referral and follow-up of TB patients。