持续肾脏替代治疗侵袭性NK/T细胞淋巴瘤并发急性肿瘤溶解综合征1例并文献复习

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收稿日期: 2013-03-11

Continuous renal replacement therapy on acute tumor lysis syndrome in an aggressive NK/T cell lymphoma: A case report and review of the literature

- Department of Hematology and Hematology Research Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, China

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Received Date: 11 March 2013

摘要: 目的：提高对急性肿瘤溶解综合征（ATLS）的认识和探讨持续肾脏替代治疗（CRRT）在其急救中的作用。方法：对1例侵袭性NK/T细胞淋巴瘤化疗后并发ATLS患者，采用CRRT救治。结果：通过CRRT，患者心力衰竭症状很快得到缓解，尿量增多，高钾、代谢性酸中毒及时得到纠正，肾功能也很快得到改善，疗效显著。结论：对于ATLS患者，如果药物疗效欠佳，应及早考虑CRRT；如果患者血流动力学不稳定，不能耐受普通血液透析治疗，CRRT应成为优先考虑的治疗选择。
- 肿瘤溶解综合征 /
- 持续肾脏替代治疗 /
- 急性肾功能衰竭
Abstract: Objective: To improve the recognition of acute tumor lysis syndrome (ATLS) and to explore the role of continuous renal replacement therapy (CRRT) in its emergency.Method: A case of ATLS in an aggressive NK/T cell lymphoma was emergently cured by CRRT.Result: After CRRT,the patient with heart failure symptoms quickly eased,urine output increased,potassium and metabolic acidosis were corrected promptly,and renal function improved quickly.Conclusion: ATLS patients should be considered early CRRT if efficacy of drugs is poor.In ATLS patients of unstable hemodynamics and intolerance for routine hemodialysis,CRRT should be a superior option.
- tumor lysis syndrome /
- continuous renal replacement therapy /
- acute renal failure

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