A case report of blood cross-matching incompatibility caused by combining IgM and IgG antibodies against E antigen
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Abstract: We analyzed a case of an elderly patient who presented with incompatibility reactions in multiple transfusions.Using quick centrifugation,classic anti-human globulin and polybrene method in erythrocyte spectrum,we identified that both IgM and IgG anti-E antibodies were present in the patient's serum.We selected the same ABO type,E-antigen negative red blood cell suspension for him,which showed no agglutination and hemolysis in the cross-matching tests.Our study suggested that for patients with only anti-E antibodies in the serum,same ABO type,E-antigen negative red blood cell suspension could be used for transfusion.
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Key words:
- anti-E IgG /
- anti-E IgM /
- cross-matching
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