新生儿溶血病与疑难交叉配血的关系

谭庆芬

doi:10.13201/j.issn.1004-2806-b.2014.06.003

新生儿溶血病与疑难交叉配血的关系

谭庆芬

- 广西血液中心(广西柳州, 545005)
基金项目:
广西卫生厅医药卫生计划课题（No：Z2013153）

详细信息

中图分类号: R556.6

收稿日期: 2013-11-05

Relationship of hemolytic disease of newborns with difficult cross-matching of blood

TAN Qingfen

- Guangxi Blood Center, Liuzhou, 545005, China

Received Date: 05 November 2013

摘要

摘要: 目的：通过对新生儿科患者配血不合血样检测结果进行分析，找出导致新生儿交叉配血不合的原因并寻求有效的解决办法。方法：通过新生儿溶血病血清学检测方法，可检测患者是由母婴红细胞血型不合引起的新生儿溶血病。结果：直接抗球蛋白试验阴性，由IgG抗-A引起配血不合4例；由IgG抗-B引起配血不合6例；直接抗球蛋白试验阳性，由IgG抗-D引起配血不合3例；由IgG抗-E引起配血不合2例。结论：ABO或Rh 血型系统的新生儿溶血病是导致临床疑难交叉配血不合的重要因素之一，配合性输注，可确保临床输血安全。
- 新生儿溶血病 /
- 疑难配血 /
- 输血
Abstract: Objective: To analyze the detection results of crossmatching incompatibility blood samples of newborns, and find the reasons of crossmatching incompatibility and the effective solutions. Method: The blood samples were detected by hemolytic disease of newborns serological detection methods, to detect hemolytic disease of newborns caused by the mother's and baby's RBC blood group incompatibility. Result: Among negative samples of direct antiglobulin test,there were 4 cases of crossmatching incompatibility caused by IgG Anti -A antibody, and 6 cases of crossmatching incompatibility caused by IgG Anti -B antibody. Among positive samples of direct antiglobulin test, there were 3 case of crossmatching incompatibility caused by IgG Anti -D antibody, and 2 cases of crossmatching incompatibility caused by IgG Anti -E antibody.Conclusion: ABO(HDN) or Rh (HDN) might be one of the important factors that lead to clinically difficult cross-matching incompatibility. Matched blood transfusion would ensure the safety of clinical transfusion.
- hemolytic disease of newborns /
- difficult blood cross-match /
- blood transfusion