-
摘要: 目的:回顾分析评价降钙素原在南京医科大学第一附属医院各临床科室的应用情况。方法:选取2016-01-01-2016-10-28南京医科大学第一附属医院17 736住院人次降钙素原检测结果进行统计分析。结果:总体阳性率为75.68%,监护病区降钙素原值及阳性率显著高于内科及外科病区,P<0.05。结论:降钙素原有鉴别感染种类,评价感染严重程度,指导抗生素使用及评价患者预后的作用,相关临床科室应根据降钙素原水平及动态变化合理应用抗生素。Abstract: Objective:To retrospectively analyze and evaluate the application of procalcitonin detection in our hospital clinical departments.Method:Atotal of 17 736 person-time procalcitonin test results were analyzed from January 1,2016 to October 28,2016 in our hospital.Result:The overall positive rate was 75.68%.The procalcitonin value and positive rate of ICU ward were significantly higher than those of medical and surgical ward (P<0.05).Conclusion:Procalcitonin can distinguish bacterial infection from non-bacterial infections,evaluate the severity of infection,guide the use and evaluation of the prognosis of the role of antibiotics,and clinical departments should rational use antibioticsbased on the dynamics PCT levels.
-
Key words:
- Procalcitonin /
- infectious diseases /
- antibiotics
-
-
[1] Hyuck Lee.Procalcitonin as a biomarker of infectious diseases[J].Korean J Intern Med,2013,28:285-291.
[2] Müller B,Becker KL.Procalcitonin:how a hormone became a marker and mediator of sepsis[J].Swiss Med Wkly,2001,131:595-602.
[3] Liew YX,Chlebicki MP,Lee W,et al.Use of procalcitonin(PCT)to guide discontinuation of antibioticuse in an unspecified sepsis is an antimicrobial stewardship program(ASP)[J].Eur J Clin Microbiol Infect Dis,2011,30:853-855.
[4] Huang SL,Lee HC,Yu CW,et al.Value of procalcitonin in differentiating pulmonary tuberculosis from other pulmonary in fections:a meta-analysis[J].Int J Tuberc Lung Dis,2014,18:470-477.
[5] Kang YA,Kwon SY,Yoon HI,et al.Role of C-Reactive Protein and Procalcitonin in Differentiationof Tuberculosis from Bacterial Community Acquired Pneumonia[J].Korean J Intern Med,2009,24:337-342.
[6] 降钙素原急诊临床应用专家共识组.降钙素原(PCT)急诊临床应用的专家共识[J].中华急诊医学杂志,2012,21(9):944-951.
[7] 钱素云,刘娟.脓毒症/严重脓毒症/脓毒性休克患儿血清白蛋白水平与预后关系的研究[J].中华儿科杂志,2012,50(3):184-187.
[8] Haubitz S,Mueller B,Schuetz P.Streamlining antibiotic therapy with procal citonin protocols:consensus and controversies[J].Expert Respir Med,2013,7:145-157.
[9] Jensen JU,Hein L,Lundgren B,et al.Procal citoninguided interventions against infections to increase early appmpriate antibiotics and improve survival in the intensive care unit:a randomized trial[J].Crit Care Med,2011,39:2048-2058.
-
计量
- 文章访问数: 246
- PDF下载数: 499
- 施引文献: 0