Abstract: Objective:To analyze the cause of the disposal of apheresis platelets,and explore the improvement measures to reduce the disposalrate and ensure the safety of blood.Method:Retrospective analysis was used to classify and analyze the data of apheresis platelet collection in Fujian blood center from 2011 to 2016.Result:A total of 48 605 cases of volunteer apheresis platelet donors were collected from 2011 to 2016 in Fujian blood center,and among which,637 cases were discarded.The total disposal rate was 1.311%.The disposal ratecaused by unqualified infectious index accounted for 63.1%(402/637).The disposal rate caused by unqualified non infectious indicators accounted for 36.9%(235/746).There was a significant difference in disposal rate between unqualified infectious index and unqualified non infectious indicators from 2011 to 2016(P<0.01).The main disposal reasons were unqualified biochemical detection(ALT),followed by a small amount of blood,nucleic acid detection positive,syphilis positive,chylous blood,HBV positive,HCV positive,RBCs contamination,HIV positive,improper operation and blood expired.Conclusion:The results showed that blood donation propaganda,correct choice of blood donors,and the screening test before blood donation could ensure the quality of blood,reduce blood disposal,which should be continued tomaintain and strengthen.At the same time,targeted control measures can reduce the risk of transfusion transmitted diseases,but also can reduce unnecessary disposal,and have an important guidingsignificance and reference value for the donor recruitment and platelet collection in future.