由ABO正反定型不符发现类孟买血型

朱永亮; 许进明; 李莺; 史丽莉; 周小玉

doi:10.13201/j.issn.1004-2806-b.2018.08.013

由ABO正反定型不符发现类孟买血型

- 1. 南京医科大学第一附属医院输血科(南京, 210029);
- 2. 江苏省血液中心研究室

详细信息

通讯作者: 周小玉,E-mail:deerzxy@163.com

中图分类号: R457.11

收稿日期: 2018-04-22

The discovery of para-bombay phenotype by ABO forward and reverse typing unconformity

- 1. Department of Blood Transfusion, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China;
- 2. Jiangsu Province Blood Center

More Information

Corresponding author: ZHOU Xiaoyu, E-mail: deerzxy@163.com

Received Date: 22 April 2018

摘要

摘要: 目的:研究类孟买血型的鉴定。方法:用血型血清学、吸收放散试验检测ABH抗原及相应抗体,并进行唾液血型物质检测以及血型基因分型最终鉴定类孟买血型。结果:常规血型血清学未检出B、H抗原、吸收放散试验检出H抗原,利用新生儿红细胞和标准红细胞与患者血清反应结果的对比检出抗H或抗HI,Lewis血型为Le(a-b+),唾液中检出B、H血型物质从而鉴定该患者血型为B_mh,和该例患者血型基因分型结果一致。结论:规范疑难血型的鉴定是发现稀有血型和保证安全输血的必要条件。
- 类孟买血型 /
- 正反定型
Abstract: Objective:To study the identification of para-Bombay phenotype.Method:The ABH antigens and corresponding antibodies were detected by blood group serology as well as absorption and dispersion test.The para-Bombay phenotype was finally identified by carrying out saliva blood group material detection and blood type genotyping.Result:B and H antigens were not detected in conventional blood genegroup serology,and H antigen was detected by absorption and dispersion test.Anti H or HI were detected by comparing the result of neonatal red blood cells responding with patient serum and that of standard red blood cells responding with patient serum.Lewis'blood type is Le(a-b+),and B and H blood type material were detected in his saliva so that the blood type of the patient was identified as B_mh,the same as the blood type genotyping result of the patient.Conclusion:It is necessary to regulate the identification of difficult blood types for finding rare blood types and ensuring safe blood transfusion.
- para-bombay phenotype /
- group typing and reverse typing

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参考文献(6)

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