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Abstract: The GLOB antigen is a system that has been renamed several times,changed several times,and was finally recognized as a systemic antigen for red blood cells by ISBT in 2010.The GLOB antigen belongs to the glycoside antigen and is synthesized with PK antigen as a precursor.This antigen is also a precursor antigen of NOR antigen,FORS antigen and LKE antigen.The GLOB antigen gene is polymorphic and generally occurs in exon 5.The GLOB antigen is a receptor for the B19 parvovirus and is involved in the red blood cell immune mechanism.The anti-GOLB1 antibody is a relatively rare antibody and has the nature of a D-L antibody and is a causative antibody for spontaneous abortion.
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