苏州地区单采血小板临床疗效及其与供者组群的相关研究

方志红; 金一鸣; 邱香

doi:10.13201/j.issn.1004-2806-b.2019.12.009

苏州地区单采血小板临床疗效及其与供者组群的相关研究

- 1. 南京中医药大学附属苏州市中医医院(江苏苏州, 215006);
- 2. 苏州市中心血站
基金项目:
苏州市“科教兴卫”青年科技项目(No:KJXW2015038)

详细信息

通讯作者: 金一鸣,E-mail:jym98121@sohu.com

中图分类号: R457.1

收稿日期: 2019-03-26

Clinical efficacy of platelet apheresis in suzhou and its correlation with donor group

- 1. Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, 215006, China;
- 2. Suzhou City Blood Center

More Information

Corresponding author: JIN Yiming, E-mail: jym98121@sohu.com

Received Date: 26 March 2019

摘要

摘要: 目的:调查分析苏州地区单采血小板的临床疗效与供者组群特点,以提高临床单采血小板的使用效果。方法:以2015-10—2017-02苏州市中医医院收治的89例(276次)输注血小板的患者为研究对象,分析比较血小板输注前后的临床疗效,对比有效输注组与无效输注组患者在基础疾病、血小板输注次数和供者组群等方面的差别,探讨影响血小板输注效果的相关因素。结果:89例患者共进行276次血小板输注,有效输注184次,有效输注率为66.7%。其中恶性肿瘤(CA)、急性白血病(AL)、骨髓增生异常综合征(MDS)、再生障碍性贫血(AA)、特发性血小板减少性紫癜(ITP)、慢性阻塞性肺疾病(COPD)、产后出血(PPH)、其他疾病(OTS)患者的血小板输注有效率分别为:76.9%、76.9%、59.6%、54.2%、62.9%、45.8%、83.3%、69.2%,不同患者血小板输注有效率比较差异有统计学意义(P＜0.05);随着输注次数增加,患者的输注有效率会下降(P＜0.05);但不同组群捐献者的单采血小板对患者的输注有效率比较差异无统计学意义(P＞0.05)。结论:输注单采血小板需有相应的适应证,应尽量减少输注次数。苏州地区针对血小板捐献者的筛查指标非常有效,血小板临床疗效与其供者组群没有相关性。
- 血小板输注 /
- 临床疗效 /
- 供者组群
Abstract: Objective:To investigate and analyze the clinical efficacy and donor group characteristics of apheresis platelet in Suzhou area,so as to improve the clinical efficacy of apheresis platelet.Method:A total of 89 patients(276 transfusions)who received platelet transfusion from October 2015 to February 2017 in Suzhou Traditional Chinese Medicine Hospital Jiangsu Province were included in the study.The clinical efficacy of platelet transfusion before and after platelet transfusion was compared.The differences between effective transfusion group and ineffective transfusion group in basic diseases,platelet transfusion times and donor groups were compared.The correlation of platelet transfusion effects was discussed.Result:A total of 276 platelet transfusions were performed in 89 patients,and 184 infusions were effective.The efficiency of platelet transfusion was 66.7%.Among them including cancer(CA),acute leukemia(AL),myelodysplastic syndrome(MDS),aplastic anemia(AA),idiopathic thrombocytopenic purpura(ITP),chronic obstructive pulmonary disease(COPD),postpartum hemorrhage(PPH),and other diseases(OTS),the effective rates of platelet transfusion were 76.9%,76.9%,59.6%,54.2%,62.9%,45.8%,83.3% and 69.2%,respectively.The effective rate of platelet transfusion in patients with different diseases was statistically significant(P＜0.05).With the increase of transfusion times,the effective rates of platelet transfusion in patients decreased(P＜0.05).However,there was no statistical difference in the effective rates of platelet transfusion among different groups of donors(P＞0.05).Conclusion:It is necessary to have appropriate indications for platelet transfusion,and the number of transfusions should be reduced as much as possible.The screening indicators for platelet donors in Suzhou are very effective,and there is no correlation between the clinical efficacy of platelets and the donor group.
- platelet transfusion /
- clinical efficacy /
- donor group

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参考文献(1)

[1]	关晓珍,贾菲,孙晓琳,等.2011-2015年单中心机采血小板临床输注合理性及有效性回顾分析[J].临床血液学杂志,2018,31(4):280-282.