Abstract: Objective:To evaluate the predictive value of preoperative and intraoperative indicators of patients and those of donors for blood transfusion during liver transplantation from organ donation after cardiac death（DCD）,and analyze the effect of intraoperative blood transfusion on the prognosis of patients. Method:A total of 150 patients who underwent DCD liver transplantation in our hospital from January 2013 to June 2018 were retrospectively analyzed.According to whether red blood cells were transfused during operation,the patients were divided into non-transfusion group and transfusion group.The preoperative,intraoperative and post-operative indicators of patients and those of donors were compared between the two groups. Result:Compared with the transfusion group,model for end-stage liver disease score,serum total bilirubin,international normalized ratio,operation time,intraoperative bleeding volume,donor body mass index,cold ischemia time,needs for nursing in intensive care unit and the hospitalization time in the non-transfusion group were lower,but white blood cell,hemoglobin,platelet,albumin and hepatitis B in the non-transfusion group were higher,and the difference was statistically significant（P＜0.05）.There was no significant difference in other indicators between the two groups（P＞0.05）.The area under the receiver operating characteristics（ROC）curve predicting intraoperative blood transfusion of intraoperative blood loss was the highest（0.919）.It showed that preoperative hemoglobin,operative time,intraoperative blood loss,body mass index of donor and cold ischemia time were independent risk factors for intraoperative blood transfusion by multivariate Logistic regression analysis.Conclusion:The preoperative,intraoperative and prognosis of liver transplantation patients without intraoperative blood transfusion are better.The preoperative indicators can not accurately and consistently predict intraoperative blood transfusion.The clinicians and blood transfusion departments should prepare blood and supervise patients according to the comprehensive situation of patients and donors.