血清总胆红素、C反应蛋白及脂蛋白a与高脂血症患者的关系研究
Relationship between expression of serum TBIL,CRP and LP（a） and progress of hyperlipidemia
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摘要: 目的:探究并分析血清总胆红素(TBIL)、C反应蛋白(CRP)及脂蛋白a表达情况与高脂血症患者病情进展的关系。方法:选取2018-01—2019-01溧阳市人民医院治疗的高脂血症患者51例,作为观察组。另选取同期检查的健康体检者52例,作为对照组。观察并记录2组患者一般资料(年龄、吸烟数量、体质指数、血糖、收缩压等情况)、血清TBIL、CRP及脂蛋白a水平,分析以上因素与高脂血症的相关性。结果:观察组高脂血症患者吸烟数量、体质指数、血糖、收缩压、TBIL、CRP、脂蛋白a等显著高于对照组(P＜0.05);经Pearson相关分析,吸烟数量、体质指数、TBIL、CRP、脂蛋白a等与血脂具有一定的相关性(P＜0.05);血糖和收缩压与高脂血症无明显相关性(P＞0.05),体质指数、TBIL、CRP、脂蛋白a是高脂血症的独立危险因素。结论:体质指数、TBIL、CRP、脂蛋白a是高脂血症的独立危险因素,值得临床注意。Abstract: Objective:To explore and analyze the relationship between the expression of total bilirubin（TBIL）,C-reactive protein（CRP）and lipoproteins a（LPa）in serum and the progress of patients with hyperlipidemia. Method:From January 2018 to January 2019,51 patients with hyperlipidemia in our hospital were selected as the observation group.Another 52 health checker were selected as the control group.The general data（age,smoking,body mass index,blood glucose,systolic blood pressure,etc.）and the levels of serum TBIL,CRP and lipoprotein a were observed and recorded.The correlation between the above factors and hyperlipidemia was analyzed. Result:Smoking,body mass index,blood glucose,systolic blood pressure,TBIL,CRP and lipoprotein a in the observation group were significantly higher than those in the control group（P＜0.05）;by Pearson correlation analysis,smoking,body mass index,TBIL,CRP and lipoprotein a had a certain correlation with blood lipid（P＜0.05）;there was no significant correlation between blood glucose and systolic blood pressure and hyperlipidemia（P＞0.05）,body mass index,TBIL,CRP and LP were independent risk factors of hyperlipidemia,which had statistical significance.Conclusion:BMI,TBIL,CRP and LP were independent risk factors of hyperlipidemia,which deserved clinical attention.
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Key words:
- hyperlipidemia /
- total bilirubin /
- lipoprotein a /
- correlation
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