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摘要: 目的:探讨原发性骨淋巴瘤(PBL)的诊断、治疗及预后。方法:报道1例确诊为PBL患者的临床资料,并结合文献复习,以提高对该病的认识。结果:采用化疗联合放疗治疗,该PBL患者对治疗敏感。结论:PBL为临床少见的结外淋巴瘤,多为弥漫大B细胞性非霍奇金淋巴瘤,预后较好。通常可见溶骨性破坏,影像学检查无特异性,早期明确诊断比较困难,确诊有赖于病理检查及免疫组织化学。治疗以放化疗联合治疗为宜。Abstract: Objective:To analyze the diagnosis,treatment and prognosis of primary bone lymphoma (PBL).Method:A case of histological confirmed PBL was reported and the relative literatures were reviewed.Result:The patient was treated with chemotherapy and irradiation,and had good response to the treatment.Conclusion:PBL are rare occured malignancies.Most cases of PBL are diffuse large B-cell lymphoma in the WHO classification of hematological malignancies.Its prognosis is good.Patients with PBL commonly present with local bone pain,soft tissue swelling,and a pathological fracture.Early diagnosis is difficult,and imaging examination has no specificity.The definite diagnosis depends on pathological examination and immunohistochemistry.Combination therapy including chemotherapy and radiotherapy is the optimal treatment for PBL.
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Key words:
- primary bone lymphoma /
- diagnosis /
- treatment
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