调控血管新生在治疗再生障碍性贫血中的作用

黄莉锋; 邓姝; 林圣云

doi:10.13201/j.issn.1004-2806.2018.01.015

调控血管新生在治疗再生障碍性贫血中的作用

- 1. 浙江中医药大学(杭州, 310000);
- 2. 浙江省中医院血液科
基金项目:
浙江省中医药科学研究基金项目(No:2016ZA080)

2016年省医药卫生一般研究计划(No:2016KYA151)

国家中医药管理局国家中医临床研究基地业务建设科研专项课题(No:JDZX2015121)

详细信息

通讯作者: 林圣云,E-mail:lsyww2012@163.com

中图分类号: R556.5

收稿日期: 2016-11-21

The role of regulating angiogenesis in the treatment of aplastic anemia

More Information

Corresponding author: LIN Shengyun, E-mail: lsyww2012@163.com

Received Date: 21 November 2016

摘要

- 再生障碍性贫血 /
- 血管新生 /
- 血管内皮生长因子 /
- Notch信号通路 /
- 间充质干细胞
Abstract: Aplastic anemia (AA) is a bone marrow hematopoietic failure disease,the immune system disorders have been considered as the main pathogenesis of the disease.In recent years,more and more studies have found that bone marrow microvascular system plays an important role in the process of disease,including occurrence,development and treatment of AA.Promoting angiogenesis was seen as a new treatment.In this article,we review the roles of vascular endothelial growth factor,mesenchymal stem cells and Notch signaling pathway in the regulation of bone marrow microvascularization and in the treatment of AA.
- aplastic anemia /
- angiogenesis /
- vascular endothelial growth factor /
- Notch signaling pathway /
- mesenchymal stem cells

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参考文献(16)

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