Application of Chinese version of functional assessment of chronic illness therapy-fatigue scale in ITP patients and analysis of factors affecting fatigue
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摘要: 目的:评价中文版慢性病治疗功能评估-疲劳量表(FACIT-F量表)在原发免疫性血小板减少症(ITP)患者中的信效度,并分析患者疲劳程度的影响因素。方法:首先向量表授权机构提出申请,获取中文版FACIT-F量表。纳入206例成人ITP患者。采用中文版FACIT-F量表、健康调查简表(SF-36)进行患者自评,记录相关临床资料。计算中文版FACIT-F量表的Cronbach'α系数、重测信度和效标关联系数,运用多因素线性回归分析筛选患者疲劳程度的影响因素。结果:206例患者中男84例,女122例,中位年龄50(18~76)岁。中文版FACIT-F量表的Cronbach'α系数为0.934,重测信度为0.971,与SF-36量表中"活力"维度的效标关联系数为0.591(P<0.01)。多因素线性回归分析显示,女性(P=0.022)及血小板计数偏低(P=0.007)是ITP患者疲劳的独立危险因素。结论:中文版FACIT-F量表信效度良好,可作为国内ITP患者疲劳的评价工具。女性ITP患者可能更易受到疲劳困扰;提升血小板计数有助于改善疲劳状态。
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关键词:
- 原发免疫性血小板减少症 /
- 疲劳 /
- 信效度 /
- 影响因素
Abstract: Objective:To evaluate the reliability and validity of the Chinese version of functional assessment of chronic illness therapy-fatigue (FACIT-F) in patients with primary immune thrombocytopenia (ITP),and to analyze the possible factors that affect the severity of fatigue.Method:We applied to the scale authority to obtain the Chinese version of FACIT-F.A total of 206 eligible adult patients with ITP were enrolled in this study.The Chinese version of FACIT-F and the short form health survey (SF-36) were used for patient self-assessment.At the same time,we recorded the patients' relevant clinical data.The Cronbach's alpha coefficient,the test-retest reliability and the criterion correlation coefficient of the Chinese version of the FACIT-F scale were calculated,and the factors affecting the patients' fatigue were screened by multivariate linear regression analysis.Result:Among 206 patients with ITP,there were 84 males and 122 females,with a median age of 50 (18-76) years.The Chinese version of the FACIT-F had a Cronbach'α of 0.934 and a test-retest reliability of 0.971,and the criterion validity with the "vitality" dimension of the SF-36 scale was 0.591 (P<0.01).Multivariate linear regression analysis showed that women (P=0.022) and low platelet counts (P=0.007) were independent risk factors for fatigue in patients with ITP.Conclusion:The Chinese version of the FACIT-F has good reliability and validity and can be used as an evaluation tool for fatigue in domestic ITP patients.Women with ITP may be more susceptible to fatigue,and increasing platelet counts can help improve fatigue.-
Key words:
- immune thrombocytopenia /
- fatigue /
- reliability and validity /
- affecting factors
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