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Abstract: CTL2 blood group antigen is the latest systemic antigen. It was confirmed and published by the International Blood Transfusion Association(ISBT) in October 2019. The gene locus, gene sequence, gene mutation and amino acid sequence of this antigen were introduced in detail. CTL2 antigen is a solute carrier transporter(SLC) SLC44 A2 in the large family of cell membrane solute carrier transporters(SLC). It is a choline transporter on the membrane and participates in choline transport inside and outside the cell membrane. It is one of the most important transporters of human body. CTL2 blood group system has two antigens, and all of them are high frequency antigens, which are closely related to blood transfusion and HDNF.
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Key words:
- CTL2 antigen /
- new blood group system /
- gene mutation site /
- exon sequence /
- amino acid sequence /
- blood transfusion
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