同种异体输血与恶性淋巴瘤患者感染的关系研究

李毓龙, 贺腊, 张正超, 等. 同种异体输血与恶性淋巴瘤患者感染的关系研究[J]. 临床血液学杂志, 2022, 35(2): 145-148. doi: 10.13201/j.issn.1004-2806.2022.02.015
引用本文: 李毓龙, 贺腊, 张正超, 等. 同种异体输血与恶性淋巴瘤患者感染的关系研究[J]. 临床血液学杂志, 2022, 35(2): 145-148. doi: 10.13201/j.issn.1004-2806.2022.02.015
LI Yulong, HE La, ZHANG Zhengchao, et al. Study on the relationship between allogeneic blood transfusion and infection in patients with malignant lymphoma[J]. J Clin Hematol, 2022, 35(2): 145-148. doi: 10.13201/j.issn.1004-2806.2022.02.015
Citation: LI Yulong, HE La, ZHANG Zhengchao, et al. Study on the relationship between allogeneic blood transfusion and infection in patients with malignant lymphoma[J]. J Clin Hematol, 2022, 35(2): 145-148. doi: 10.13201/j.issn.1004-2806.2022.02.015

同种异体输血与恶性淋巴瘤患者感染的关系研究

详细信息
  • 中图分类号: R551

Study on the relationship between allogeneic blood transfusion and infection in patients with malignant lymphoma

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  • 表 1  输血组与非输血组患者资料比较 例(%),X±S

    输血组
    (36例)
    非输血组
    (126例)
    P
    年龄/岁 48.6±8.4 42.1±7.3 < 0.05
    住院天数/d 47.3±11.2 19.6±8.8 < 0.05
    性别 < 0.05
      男 14(38.9) 79(62.7)
      女 22(61.1) 47(37.3)
    临床分期 < 0.05
      Ⅰ~Ⅱ期 6(16.7) 60(47.6)
      Ⅲ~Ⅳ期 30(83.3) 66(52.4)
    是否有侵入性治疗 < 0.05
      是 24(66.7) 19(15.1)
      否 12(33.3) 107(84.9)
    是否使用抗菌药物 < 0.05
      是 28(77.8) 27(21.4)
      否 8(22.2) 99(78.6)
    是否放疗或化疗 < 0.05
      是 28(77.8) 2(1.6)
      否 8(22.2) 124(98.4)
    下载: 导出CSV

    表 2  感染组与非感染组患者资料比较 例(%),X±S

    感染
    (51例)
    无感染
    (111例)
    P
    年龄/岁 45.1±10.3 44.2±7.9 >0.05
    住院天数/d 38.5±12.4 26.3±8.3 < 0.05
    性别 >0.05
      男 28(54.9) 65(58.6)
      女 23(45.1) 46(41.4)
    临床分期 >0.05
      Ⅰ~Ⅱ期 20(39.2) 46(41.4)
      Ⅲ~Ⅳ期 31(60.8) 65(58.6)
    是否有侵入性治疗 >0.05
      是 17(33.3) 26(23.4)
      否 34(66.7) 85(76.6)
    是否使用抗菌药物 >0.05
      是 16(31.4) 39(35.1)
      否 35(68.6) 72(64.9)
    是否放疗或化疗 < 0.05
      是 22(43.1) 8(7.2)
      否 29(56.9) 103(92.8)
    下载: 导出CSV

    表 3  输血与感染的优势比较 例(%)

    感染 输血组
    (36例)
    非输血组
    (126例)
    P OR 95%CI

    20(55.6)
    16(44.4)
    31(24.6)
    95(75.4)
    0.001 3.83 1.77~8.29
    下载: 导出CSV

    表 4  感染多变量logistic回归分析 例(%)

    感染 OR
    (调整后)
    P 95%CI
    年龄(< 45 vs ≥45) 1.21 0.75 0.68~3.33
    性别(男vs女) 1.12 0.76 0.65~3.05
    住院天数(< 30 vs ≥30) 1.45 0.14 0.88~3.45
    临床分期(Ⅰ~Ⅱ vs Ⅲ~Ⅳ) 1.22 0.72 0.65~3.18
    输血vs未输血 3.66 0.01 1.51~8.74
    侵入性治疗 1.43 0.18 0.85~2.76
    使用抗菌药物 1.37 0.25 0.81~2.99
    放疗或化疗 2.95 0.03 1.26~5.94
    下载: 导出CSV
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出版历程
收稿日期:  2021-03-10
刊出日期:  2022-02-01

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