成人急性髓细胞白血病的诊断与治疗进展

金洁, 周一乐. 成人急性髓细胞白血病的诊断与治疗进展[J]. 临床血液学杂志, 2022, 35(5): 309-311. doi: 10.13201/j.issn.1004-2806.2022.05.002
引用本文: 金洁, 周一乐. 成人急性髓细胞白血病的诊断与治疗进展[J]. 临床血液学杂志, 2022, 35(5): 309-311. doi: 10.13201/j.issn.1004-2806.2022.05.002
JIN Jie, ZHOU YIle. Progress in diagnosis and treatment of acute myeloid leukemia in adult[J]. J Clin Hematol, 2022, 35(5): 309-311. doi: 10.13201/j.issn.1004-2806.2022.05.002
Citation: JIN Jie, ZHOU YIle. Progress in diagnosis and treatment of acute myeloid leukemia in adult[J]. J Clin Hematol, 2022, 35(5): 309-311. doi: 10.13201/j.issn.1004-2806.2022.05.002

成人急性髓细胞白血病的诊断与治疗进展

  • 基金项目:
    国家自然科学基金国际合作重点项目(No:81820108004);国家自然科学基金(No:82170144-H0809);浙江省科学技术厅重大项目(No:491010+J3210NZJ)
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    作者简介:

    金洁,医学博士,浙江大学二级教授、主任医师、博士生导师,享受国务院特殊津贴。全国三八红旗手、全国卫生系统先进工作者、浙江大学好医生。现任浙江大学医学院附属一院血液科名誉主任、学科带头人、浙江省血液肿瘤(诊治)重点实验室主任,国家卫健委临床重点学科-血液病学科带头人,浙江省血液病临床医学研究中心主任、浙江大学癌症研究院恶性血液病基础与临床研究团队负责人。中国女医师协会血液肿瘤专委会主任委员、CSCO抗白血病联盟副主任委员、CSCO抗淋巴瘤联盟常务委员、中国抗癌协会整合血液病副主任委员、中国医师协会血液病医师分会常务委员、海峡两岸血液病专委会常务委员、浙江省医师协会血液病分会会长、中国抗癌协会血液病转化专委会名誉主任委员。以第一完成人获得2011年国家科技进步二等奖1项、浙江省科学技术进步奖一等奖2项、二等奖4项。以第一与通讯作者(共同)在Lancet OncolCellJCOBloodLeukemiaJHO等国际期刊上发表SCI论文170余篇

    通讯作者: 金洁,E-mail:jiej0503@zju.edu.cnjiej0503@163.com
  • 中图分类号: R733.71

Progress in diagnosis and treatment of acute myeloid leukemia in adult

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  • [1]

    Shallis RM, Wang R, Davidoff A, et al. Epidemiology of acute myeloid leukemia: Recent progress and enduring challenges[J]. Blood Rev, 2019, 36: 70-87. doi: 10.1016/j.blre.2019.04.005

    [2]

    DiNardo CD, Jonas BA, Pullarkat V, et al. Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia[J]. N Engl J Med, 2020, 383(7): 617-629. doi: 10.1056/NEJMoa2012971

    [3]

    Maiti A, DiNardo CD, Qiao W, et al. Ten-day decitabine with venetoclax versus intensive chemotherapy in relapsed or refractory acute myeloid leukemia: A propensity score-matched analysis[J]. Cancer, 2021, 127(22): 4213-4220. doi: 10.1002/cncr.33814

    [4]

    DiNardo CD, Lachowiez CA, Takahashi K, et al. Venetoclax combined with FLAG-IDA induction and consolidation in newly diagnosed and relapsed or refractory acute myeloid leukemia[J]. J Clin Oncol, 2021, 39(25): 2768-2778. doi: 10.1200/JCO.20.03736

    [5]

    Kadia TM, Reville PK, Borthakur G, et al. Venetoclax plus intensive chemotherapy with cladribine, idarubicin, and cytarabine in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a cohort from a single-centre, single-arm, phase 2 trial[J]. Lancet Haematol, 2021, 8(8): e552-e561. doi: 10.1016/S2352-3026(21)00192-7

    [6]

    Hills RK, Castaigne S, Appelbaum FR, et al. Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials[J]. Lancet Oncol, 2014, 15(9): 986-996. doi: 10.1016/S1470-2045(14)70281-5

    [7]

    Fournier E, Duployez N, Ducourneau B, et al. Mutational profile and benefit of gemtuzumab ozogamicin in acute myeloid leukemia[J]. Blood, 2020, 135(8): 542-546. doi: 10.1182/blood.2019003471

    [8]

    Stone RM, Mandrekar SJ, Sanford BL, et al. Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation[J]. N Engl J Med, 2017, 377(5): 454-464. doi: 10.1056/NEJMoa1614359

    [9]

    Roboz GJ, Strickland SA, Litzow MR, et al. Updated safety of midostaurin plus chemotherapy in newly diagnosed FLT3 mutation-positive acute myeloid leukemia: the RADIUS-X expanded access program[J]. Leuk Lymphoma, 2020, 61(13): 3146-3153. doi: 10.1080/10428194.2020.1805109

    [10]

    Schlenk RF, Weber D, Fiedler W, et al. Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD[J]. Blood, 2019, 133(8): 840-851. doi: 10.1182/blood-2018-08-869453

    [11]

    Perl AE, Martinelli G, Cortes JE, et al. Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML[J]. N Engl J Med, 2019, 381(18): 1728-1740. doi: 10.1056/NEJMoa1902688

    [12]

    DiNardo CD, Stein EM, de Botton S, et al. Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML[J]. N Engl J Med, 2018, 378(25): 2386-2398. doi: 10.1056/NEJMoa1716984

    [13]

    Pollyea DA, Tallman MS, de Botton S, et al. Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia[J]. Leukemia, 2019, 33(11): 2575-2584. doi: 10.1038/s41375-019-0472-2

    [14]

    Stein EM, DiNardo CD, Pollyea DA, et al. Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia[J]. Blood, 2017, 130(6): 722-731. doi: 10.1182/blood-2017-04-779405

    [15]

    Cortes JE, Heidel FH, Hellmann A, et al. Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome[J]. Leukemia, 2019, 33(2): 379-389. doi: 10.1038/s41375-018-0312-9

    [16]

    Garcia-Manero G, Gore SD, Cogle C, et al. Phase Ⅰ study of oral azacitidine in myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia[J]. J Clin Oncol, 2011, 29(18): 2521-2527. doi: 10.1200/JCO.2010.34.4226

    [17]

    Wei AH, Döhner H, Pocock C, et al. Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission[J]. N Engl J Med, 2020, 383(26): 2526-2537. doi: 10.1056/NEJMoa2004444

    [18]

    Lancet JE, Uy GL, Cortes JE, et al. CPX-351(cytarabine and daunorubicin)Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia[J]. J Clin Oncol, 2018, 36(26): 2684-2692. doi: 10.1200/JCO.2017.77.6112

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出版历程
收稿日期:  2022-04-19
刊出日期:  2022-05-01

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