Short-term extensive extramedullary and intramedullary relapse of acute lymphoblastic leukemia with 11q23/MLL gene rearrangement: a case report and literature review
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Abstract: A case of short-term extensive extramedullary and intramedullary relapse of acute lymphoblastic leukemia with 11q23/MLL gene rearrangement was reported and related literature were reviewed.Clinical manifestations,laboratory findings,diagnosis and treatment of the patient were analyzed.The patient had acute onset,rapid progression,short survival and poor results after multiple chemotherapy.MLL-related leukemia is a disease with complicated clinical manifestations.Early diagnosis,timely development of a more reasonable and individual program is the key to improve the prognosis.
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Key words:
- acute lymphoblastic leukemia /
- relapse /
- marrow /
- extramedullary
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