Result analysis of whole blood tissue factor procoagulant activity, plasma D-dimer and B-type natriuretic peptide in myocardial infarction patients
-
摘要: 目的:探讨急性心肌梗死(AMI)患者全血组织因子凝血活性(TF-PCA)、血浆D-二聚体(DD)及B型脑钠肽(BNP)的水平变化及其临床意义。方法:应用仪器法对63例AMI患者及61例正常对照组进行全血TF-PCA和血浆DD及BNP水平的检测,并进行比较。结果:AMI患者全血TF-PCA、血浆DD和BNP检测结果均显著高于正常对照组(P<0.01)。结论:TF-PCA、DD和BNP对AMI患者的病情预测和早期诊治有重要的临床意义。Abstract: Objective: To investigate the changes and clinical significance of the whole blood tissue factor procoagulant activity (TF-PCA),plasma D-dimer and B-type natriuretic peptide (BNP).Method: The TF-PCA,plasma D-dimer and BNP levels of 63 patients with acute myocardial infarction and 61 cases of normal control group were detected and compared.Result: The three detection indicators in patients with acute myocardial infarction were significantly higher than those in the normal control group (P<0.01).Conclusion: TF-PCA,D-dimer and BNP would have important clinical significance for disease prediction,early diagnosis and treatment of patients with acute myocardial infarction.
-
Key words:
- acute myocardial infarction /
- TF-PCA /
- D-dimer /
- BNP
-
-
[1] 刘国华,骆峰,夏志宏,等.急性心肌梗死患者心率震荡现象及其临床意义[J].临床心血管病杂志,2006,22(8):466-468.
[2] 廖肇发.心脏型脂肪酸结合蛋白在急性心肌梗死的早期诊断价值[J].国际医药卫生导报,2008,14(16):26-28.
[3] 严蜀华,李素君,叶青跃,等.脑梗死患者血清同型半胱氨酸、超敏C反应蛋白水平和全血细胞组织因子促凝活性的检测分析[J].微循环学杂志,2012,22(1):64-65.
[4] 董明国,杜忠芳,程静,等.慢性脑血管病治疗前后血液流变学指标和全血组织因子活性的变化[J].微循环学杂志,2010,20(4):49-50.
[5] 孔祥阳,牛麦玲,韩瑜,等.急性冠状动脉综合征患者血清高敏C反应蛋白及脑钠肽和D-二聚体水平变化[J].中华实用诊断与治疗杂志,2012,26(5):480-481.
[6] TALWAR,SQUIRE I B,DOWNIE P F,et al.Plasma N terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina[J].Heart,2000,84:421-424.
[7] KIKUTA K,YASUE H YOSHUMURA M,et al.Increase plasma level of B-type natriutetide peptide in patients with unstable angina[J].Am Heart J,1996,132:101-107.
[8] MAGGA J,PUHAKKA M,HIETAKORPI S,et al.Atrial natriuretic peptide,B-type natriuretic peptide and serum collagen markers after acute myocardial infarction[J].J Appl Phsiol,2004,96:1306-1311.
-
计量
- 文章访问数: 46
- PDF下载数: 50
- 施引文献: 0