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摘要: 目的：分析意外抗体在ABO血型鉴定中的干扰作用，为ABO疑难血型鉴定提供思路和对策。方法：对全自动血型仪检测的ABO血型正反定不合的样本结合盐水试管法、抗体筛查及鉴定结果以及病史资料综合分析。结果：26例引起正反定不合的抗体中IgM 18例，IgG 8例，分别是抗-M 10例、抗-Lea 2例、抗-N 1例、抗-P1 2例、抗-JKa 1例、抗-D 2例、抗-E 2例、抗-C 1例、抗-c 1例、抗-Fya 1例、自身抗体3例。结论：IgM和IgG两类意外抗体均能引起ABO血型正反定不合，反定细胞应该选用常见意外抗体对应抗原表位缺失的红细胞。Abstract: Objective: To analyze the interference of unexpected antibodies in ABO blood group identification and give some ideas to solve the problem.Method: Combined the conventional tube test,antibody screening and identification and patients' clinic history records to analyze ABO discrepancy results detected by automatic blood group analyzer.Result: Among these 26 discrepancy results of ABO blood group,there were 10 cases with anti-M,2 anti-Lea,2 anti-P1,2 anti-D and 2 anti-E respectively,1 case with anti-N,anti-JKa,anti-C,anti-c and anti-Fya respectively,and other 3 cases were cold autoantibodies.Conclusion: Unexpected antibodies of IgM and IgG could both cause discrepancy of ABO blood group and red blood cells selected to determine reverse blood group should lack corresponding epitopes.
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Key words:
- unexpected antibodies /
- ABO blood group identification
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[1] 胡丽华.临床输血检验[M].2版北京:中国医药科技出版社,2010:24-25,50-51.
[2] 范金波,李海平,刘久波.8967例手术前备血及受血者不规则抗体检测结果分析[J].临床输血与检验,2011,13(2):155-156.
[3] 王蓝鸽,周金安,魏晴.不规则抗体影响血型鉴定的处理和分析[J].临床血液学杂志(输血与检验),2009,22(6):318-320.
[4] 任本春,池泉.献血者红细胞血型不规则抗体筛查必要性的探讨[J].中国输血杂志,2010,23(2):126-127.
[5] JOHN D ROBACK,MARTHA RAE COMBS,BRENDA J,et al.Technical Manual[M].16th ed.Bethesda,MD:American Association of Blood Banks(AABB),2008:229-347.
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