Investigation of ABO subtype and weak D on blood donors in Dongguan
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摘要: 目的：分析无偿献血者ABO亚型和弱D型的分布特点。方法：对2009-01-01-2012-12-31在我市参加无偿献血的197 146名献血者血样进行ABO、RhD血型鉴定，若ABO正反定型不一致及有弱凝集等反应特点的样本进行确认试验，鉴定为ABO亚型者确定亚型分型；对RhD阴性及有弱凝集反应者进行弱D型确认试验。结果：在197 146名献血者中共检出ABO亚型30例，其中A亚型5例，B亚型12例，AB亚型7例，类孟买型6例；除A2、A2B和类孟买型外，ABO亚型的检出率为0.011%；共检出弱D型28例，检出率为0.014%。结论：我市无偿献血者中ABO亚型频率偏低，B亚型明显多于A亚型；弱D型频率明显低于国外报道，与国内报道相似。Abstract: Objective: To analyze the distribution characteristics of ABO subtype and weak D on blood donors.Method: A total of 197 146 cases of blood donors' samples were collected from Jan.1, 2009 to Dec.31,2012. ABO and RhD group were detected. If ABO group typing and reverse typing were inconsistent and RhD had weak agglutination reactions, ABO subtype classification and weak D were determined. Result: In 197 146 donors' samples, 30 cases of ABO subtype were detected, including 5 cases of A subtype, 12 cases of subtype B, 7 cases of AB subtype, and 6 cases of para-Bombay. In addition to the A2 subtype, A2B subtype and para-Bombay, the frequency of ABO subtype were 0.011%. 28(0.014%) cases of weak D were detected. Conclusion: ABO subtype frequencies of blood donors were low in our city. B subtypes were significantly more than A subtypes. The frequency of weak D was significantly lower than that of abroad reports, but same as that of the domestic reports.
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