超敏CRP联合降钙素原检测在儿童急性上呼吸道感染中的应用

吴皖; 周珣

doi:10.13201/j.issn.1004-2806-b.2014.06.017

超敏CRP联合降钙素原检测在儿童急性上呼吸道感染中的应用

吴皖,
周珣^,

- 孝感市中心医院检验科(湖北孝感, 432000)

详细信息

通讯作者: 周珣,E-mail:1783811055@qq.com

中图分类号: R517.6

收稿日期: 2013-08-23

Application of high sensitivity C reactive protein and procalcitonin to children with acute upper respiratory tract infection

WU Wan,
ZHOU Xun^,

- Xiaogan Central Hospital, Xiaogan, 432000, China

More Information

Corresponding author: ZHOU Xun, E-mail: 1783811055@qq.com

Received Date: 23 August 2013

摘要

摘要: 目的：探讨超敏CRP（hs-CRP）联合降钙素原（PCT）检测在儿童急性上呼吸道感染性疾病早期鉴别诊治中的应用价值。方法：对211例儿童急性上呼吸道感染性患者采集静脉血同时进行hs-CRP和PCT检测。根据病原学诊断结果将患儿分为细菌感染组85例和病毒感染组126例。同时选取健康体检儿童100例为对照组，对各组结果进行比较。结果：细菌感染组hs-CRP、PCT均显著高于病毒感染组85例和健康对照组（r=0.861，P<0.01），病毒感染组与健康对照组hs-CRP、PCT比较差异无统计学意义（P>0.05）。结论：hs-CRP联合PCT检测可作为儿童急性上呼吸道感染早期鉴别诊断的敏感指标。
- 超敏CRP /
- 降钙素原 /
- 急性上呼吸道感染
Abstract: Objective: To discuss the value of combined detection of high-sensitivity C reactive protein (hs-CRP) with procalcitonin (PCT) in the early diagnosis and treatment about the disease of acute upper respiratory infection in children.Method: The levels of serum CRP and PCT of 211 children with acute upper respiratory tract inflection were detected. The patients were divided into bacterial infection group and viral infection group on the basis of etiological diagnosis results, and 100 healthy children were selected as control group. The results of each group were compared.Result: The levels of CRP and PCT of bacterial infection group were higher than those of viral infection group and the control group, the results emerged a positive correlation (r=0.861, P<0.01). The cases included in the analysis which showed no significant difference (P>0.05) for the viral infection group and the control group.Conclusion: Combined detection of hs-CRP with PCT could be used as a sensitive index for early differential diagnosis of children with acute upper respiratory tract infection.
- hs-CRP /
- PCT /
- acute upper respiratory tract infection

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参考文献(8)

[1]	JAYE D L, WAITES K B. Clinical application of hsCRP in pediatrics[J]. Pediatr Infect Dis J,1997,16:735-736.
[2]	丁勇,陈伟,杨立山.降钙素原在急诊抗感染中的临床应用及诊断意义[J].宁夏医学杂志,2012,34(6):500-501.
[3]	褚福棠.实用儿科学[M].7版.北京:人民卫生出版社,2008:116721170.
[4]	汤明霞.血超敏C反应蛋白检测对诊断新生儿感染的意义[J].临床肺科杂志,2010,15(2):189-190.
[5]	杨惠聪,原敏,杨彩娥.超敏C-反应蛋白(hs-CRP)检测在儿科细菌性感染性疾病中的应用价[J].现代诊断与治疗,2009,20(5):268-270.
[6]	王丽芬,李宗英.超敏C反应蛋白检测的临床意义[J].按摩与康复医学,2010,35(12):61.
[7]	NAHER B S, MANNAN M A, NOOR K, et al. Role of serum procalcitonin and C-reactive protein in the diagnosis of neonatal sepsis[J]. Bangladesh Med Res Counc Bull,2011,37:40-46.
[8]	邹国英,任碧琼,徐飞,等.革兰阴性菌感染患者降钙素原的测定[J].国际检验医学杂志,2010,31(5):494-495.