HCV RNA病毒载量和肝功能及白蛋白的相关性研究

邵林楠; 张树婷; 段莹; 肖南; 于卫建; 刘铭; 周世航

doi:10.13201/j.issn.1004-2806-b.2018.08.007

HCV RNA病毒载量和肝功能及白蛋白的相关性研究

- 1. 大连市血液中心血型室(辽宁大连, 116001);
- 2. 大连医科大学细胞生物学教研室

详细信息

通讯作者: 刘铭,E-mail:liuminglinxi@163.com; 周世航,E-mail:zshsail@163.com

中图分类号: R512.6

收稿日期: 2018-03-09

Study on correlation between HCV RNA viral load and liver function and ALB

- 1. Dalian Blood Center, Dalian, 116001, China;
- 2. Department of Cell Biology, Dalian Medical University

More Information

Corresponding authors: LIU Ming ; ZHOU Shihang, E-mail: zshsail@163.com

Received Date: 09 March 2018

摘要

摘要: 目的:研究血液中丙型肝炎病毒核糖核酸(HCV RNA)载量与肝功能及白蛋白(ALB)等指标间的相关性,探讨病毒含量和肝组织损伤之间的关系。方法:选取193例大连地区汉族人群HCV感染患者为研究对象,检测血液中HCV RNA病毒载量,同时测定谷丙转氨酶(ALT)、谷草转氨酶(AST)、AST/ALT及ALB等指标。用豆形图展示HCV RNA病毒载量数据,分析HCV RNA载量与各指标间的相关性。结果:不同性别组HCV RNA载量分布差异无统计学意义(P>0.05);HCV RNA载量与年龄不存在显著的相关性(P>0.05)。HCV RNA载量与ALT、AST、AST/ALT及ALB均不相关(P>0.05)。根据受试者HCV RNA载量数量级将其分为4组,ALT、AST、AST/ALT及ALB在各组间差异无统计学意义(P>0.05)。结论:大连地区汉族人群HCV患者血液中HCV RNA载量与ALT、AST、AST/ALT及ALB等指标不相关,HCV RNA病毒载量不能反映肝脏损伤程度。
- 丙型肝炎病毒 /
- 谷丙转氨酶 /
- 谷草转氨酶 /
- 白蛋白
Abstract: Objective:To investigate the relationship between HCV RNA load and liver function and ALB in HCV infected patients.Method:The HCV RNA viral load and ALT,AST,AST/ALT and ALB were measured in 193 Dalian Han HCV infected patients.The HCV RNA viral load data were presented by beanplots,and the correlations between HCV RNA load and each index were analyzed.Result:Gender and age could not affect HCV RNA viral load in HCV infected patients.HCV RNA viral load was not correlated with ALT,AST,AST/ALT and ALB.In addition,we divided the patients into four groups according to HCV RNA viral load,and ALT,AST,AST/ALT and ALB were not significantly different among the groups.Conclusion:Our results showed that HCV RNA load in Dalian Han HCV infected patients was not related to ALT,AST,AST/ALT and ALB,that is,the HCV RNA load could not reflect the degree of liver injury.
- hepatitis C virus /
- ALT /
- AST /
- ALB

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