健康人群骨代谢标志物分析

张新伟; 李金奎; 汤海燕; 潘倩; 杜斌

doi:10.13201/j.issn.1004-2806-b.2018.10.017

健康人群骨代谢标志物分析

- 武汉市黄陂区人民医院检验科(武汉, 430300)
基金项目:
湖北省卫生和计划生育委员会科研项目(No:WJ2017F045)

详细信息

通讯作者: 张新伟,E-mail:ZXWZY1201@sina.com

中图分类号: R591

收稿日期: 2018-04-08

Analyzation on the level of biomarker of bone metabolism in health population

- Department of Clinical Laboratory, Huangpi District People's Hospital, Wuhan, 430300, China

More Information

Corresponding author: ZHANG Xinwei, E-mail: ZXWZY1201@sina.com

Received Date: 08 April 2018

摘要

摘要: 目的:分析健康人群不同性别、不同年龄间的骨代谢标志物水平。方法:用化学发光法检测549例健康人群骨钙素(BGP)、I型胶原氨基端肽原(PINP)、β-异构C-端肽(β-CTX)、甲状旁腺素(PTH)等骨代谢标志物水平,并对不同性别、不同年龄间的结果进行比较分析。结果:在健康人群中,男性51~60岁组和 ≥ 60岁组PINP和β-CTX明显升高(P<0.05), ≥ 60岁组BGP明显升高(P<0.05);女性51~60岁组和 ≥ 60岁组BGP、PINP、β-CTX和PTH明显升高(P<0.05)。结论:健康人群不同性别、不同年龄间的骨代谢标志物水平存在明显不同。
- 骨钙素 /
- I型胶原氨基端肽原 /
- β-异构C-端肽 /
- 甲状旁腺素
Abstract: Objective:To analyze the level of biomarker of bone metabolism in different sex and age health population. Method:The BGP,PINP,β-CTX and PTH level were detected by chemiluminescent immunoassay in health population,and analyzed in different sex and age group. Result:In health man,the level of PINP and β-CTX in 51-60 years and ≥ 60 years groups,BGP in ≥ 60 years group were significantly higher than ≤ 30 years group.In health female,the level of BGP,PINP,β-CTX and PTH in 51-60 years and ≥ 60 years groups were significantly higher than ≤ 30 years group.Conclusion:The level of biomarker of bone metabolism in different sex and age health population were significantly different.
- bone glutamyl protein /
- procollagen type Ⅰ N-terminal propeptide /
- beta-isomerized C-telopeptide /
- parathyroid hormone

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