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摘要: 目的：分析1例Rh（D）阴性患者血清中弱D强E抗体产生的可能原因，并探索类似病例的安全输血方案。方法：回顾性分析1例ORh（D）阴性患者交叉配血试验结果及该患者的一般资料，后续系列血清学实验室相关方法。结果：证实该患者血清中IgG类抗-D、抗-E联合并存，且抗-D（效价1：64）弱于抗-E（效价1：512）。筛选Rh分型无D和E抗原的ABO同型红细胞悬液给予患者输注。结论：Rh分型检测符合临床发展的需求，对解决相关特殊群体的临床用血难题和降低疑难配血的频率意义重大。Abstract: Objective: To analyze the possible causes of weak D strong E antibody in the serum of a Rh(D) negative patient, and explore a safe transfusion scheme for similar cases.Method: A retrospective analysis of the results of a cross-matching test in a patient with ORh(D) negative and general information of the patient were carried out, as well as a series of serological laboratory related methods.Result: It was confirmed that the IgG class of anti-D and anti-E in the serum of the patient coexisted, and the anti-D(titer 1:64) was weaker than the anti-E(titer 1:512).We screened Rh-type ABO homologous red cell suspensions without D and E antigens for infusion into patients.Conclusion: Rh typing detection would meet the needs of clinical development, and it may be of great significance to solve the clinical blood problem of related special groups and reduce the frequency of difficult blood matching.
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Key words:
- Rh(D)negative /
- weak D-strong E antibody /
- blood transfusion
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