TEG检测孕妇血液不同稀释状态下凝血功能的变化规律

苗伶俐; 申改香; 孙海潮; 赵乐; 王建睿; 吴继博

doi:10.13201/j.issn.1004-2806-b.2019.10.012

TEG检测孕妇血液不同稀释状态下凝血功能的变化规律

- 1. 榆林市星元医院输血科(陕西榆林, 719000);
- 2. 西安交通大学第一附属医院输血科
基金项目:
榆林市科学技术研究与开发项目(No:4-50502)

详细信息

通讯作者: 吴继博,E-mail:260006102@qq.com

中图分类号: R457.1

收稿日期: 2019-03-17

Investigation on changes of coagulation function in pregnant women with different blood dilution by TEG

- 1. Department of Blood Transfusion, Xing Yuan Hospital of Yulin, Yulin, 719000, China;
- 2. Department of Blood Transfusion, First Affiliated Hospital of Xi'an Jiaotong University

More Information

Corresponding author: WU Jibo, E-mail: 260006102@qq.com

Received Date: 17 March 2019

摘要

摘要: 目的:探讨孕妇血液在不同的稀释状态下凝血功能的变化规律。方法:选取正常孕妇60例(早孕、中孕、晚孕各20例),采集静脉血并用0.9 % NaCl分别进行20%、40%、60%、80%稀释后进行血栓弹力图(TEG)检测,并对TEG各指标进行统计学分析。结果:早孕组与晚孕组未稀释标本的R、K值结果比较均差异有统计学意义,早孕组、中孕组、晚孕组稀释度为80%时R值结果正常或偏低,与其余稀释度结果之间差异有统计学意义。早、中孕组稀释度＞40%,晚孕组稀释度＞60%时K值结果增高,并与未稀释标本结果比较差异有统计学意义;早孕组、中孕组、晚孕组稀释度＞40%时MA值结果偏低,并与未稀释标本结果差异有统计学意义。早孕组、中孕组、晚孕组未稀释标本综合凝血指数(CI)结果之间均差异有统计学意义,早孕组稀释度≥60%,中孕组、晚孕组稀释度≥80%时CI值结果偏低,并与各稀释度结果之间均差异有统计学意义。结论:早孕、中孕、晚期孕妇血液均呈高凝状态,并随孕期延长呈正相关,早孕组血液稀释度为60%以上时,中孕、晚孕组血液稀释度为80%时CI减低。
- 孕妇 /
- 血液稀释度 /
- 凝血功能 /
- 血栓弹力图
Abstract: Objective:To investigate the changes of blood coagulation function in pregnant women under different dilution conditions.Method:60 normal pregnant women in our hospital(20 cases in early pregnancy,20 cases in middle pregnancy and 20 cases in late pregnancy)were selected.Venous blood was collected and diluted with 0.9% NaCl for 20%,40%,60% and 80% respectively.Thromboelastography(TEG)was performed.Statistical analysis of TEG indicators was carried out.Result:The results of R and K values of undiluted samples in early pregnancy group and late pregnancy group had statistical significance.The results of R values in early pregnancy group,middle pregnancy group and late pregnancy group were normal or low when the dilution was 80%.There was statistical significance between the results of R values and other dilutions.The results of K value increased when the dilution was more than 40% in the early and middle pregnancy group and 60% in the late pregnancy group,and had statistical significance compared with the results of undiluted samples.The results of MA value were lower when the dilution was more than 40% in the early pregnancy group,the middle pregnancy group and the late pregnancy group,and had statistical significance compared with the results of undiluted samples.The CI values of undiluted samples in early pregnancy group,middle pregnancy group and late pregnancy group were significantly lower than those in early pregnancy group(＞60%)and middle pregnancy group(＞80%)and late pregnancy group(＞80%).Conclusion:The blood of early,middle and late pregnant women is hypercoagulable and positively correlated with the prolongation of pregnancy.When the blood dilution of early pregnant women is more than 60%,the comprehensive coagulation index(CI)decreases when the blood dilution of middle and late pregnant women is 80%.
- pregnant women /
- blood dilution /
- coagulation function /
- thrombocyte attempt

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