2011-2012年南京地区无偿献血人群丙型肝炎病毒感染情况分析

朱绍汶; 陈显; 王金花; 王跃帮; 林红

2011-2012年南京地区无偿献血人群丙型肝炎病毒感染情况分析

- 江苏省血液中心(南京, 210042)
基金项目:
江苏省卫生厅科技项目（No：H201225）；江苏省预防医学会科技项目（No：Y2012002）

详细信息

通讯作者: 林红,E-mail:linhong712003@yahoo.com.cn

中图分类号: R512.6

收稿日期: 2013-01-10

Prevalence of hepatitis C virus infections among voluntary blood donors in Nanjing

- Jiangsu Province Blood Centre, Nanjing, 210042, China

More Information

Corresponding author: LIN Hong, E-mail: linhong712003@yahoo.com.cn

Received Date: 10 January 2013

摘要

摘要: 目的：了解南京地区无偿献血人群丙型肝炎病毒（HCV）感染情况。方法：收集2011-2012年129 328份无偿献血者的血液标本进行ELISA双试剂抗-HCV检测以及混样核酸检测，并对其结果进行统计分析。结果：2011-2012年南京地区无偿献血者的抗-HCV阳性率为0.25%（327/129 238），HCV RNA阳性率为0.10%（130/129 238）。丙肝病毒的感染与性别和受教育程度不相关（P>0.05），但与献血者的年龄、职业密切相关（P<0.05）；同时抗-HCV阳性率与ALT、HCV RNA之间具有一定的相关性，但与乙肝病毒、艾滋病病毒和梅毒感染无关。结论：南京地区无偿献血人群中抗-HCV阳性率较低，且主要为单纯性感染。
- 无偿献血者 /
- 丙型肝炎病毒 /
- 血清学筛查 /
- 核酸检测
Abstract: Objective: To investigate the prevalences of anti-HCV and HCV RNA among volunteer blood donors in Nanjing.Method: A total of 129 328 blood samples from volunteer blood donors were recruited from January 2011 to December 2012 in Jiangsu.The anti-HCV assays were performed by ELISA with reagents from two different manufactures and HCV RNA were detected by nucleic acid amplification test with Roche combas s 201.The results were analyzed statistically.Result: Anti-HCV positive rate among volunteer blood donors in Jiangsu was 0.25%(327/129328).HCV RNA positive rate was 0.10%(130/129 328).There was statistical significance in different ages and occupations and no significance in gender and education level.Conclusion: The anti-HCV prevalence is relatively low among volunteer blood donors and HCV infection is mainly simple infection in Nanjing.
- volunteer blood donors /
- HCV /
- anti-HCV /
- HCV RNA

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参考文献(12)

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