Antimicrobial resistance of Acinetobacter baumanii causing nosocomial infection in brain surgery
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摘要: 目的：探讨医院感染鲍曼不动杆菌（ABA）的耐药现状，为临床医师控制脑外科医院感染提供参考依据。方法：202株ABA培养与鉴定严格按《全国临床检验操作规程》，采用常规方法进行；抗菌药物敏感试验采用CLSI推荐的纸片扩散法（KB法），依据CLSI2009-2011年的折点判读药敏结果。结果：脑外科流行的ABA在呼吸道标本中检出率最高，达到68.3%。药敏数据结果显示：ABA对临床常用的抗菌药物均产生了严重的耐药性，耐亚胺培南ABA检出率为27.2%，泛耐药ABA菌株检出率为15.8%。结论：脑外科应重视感染病原学检测，加强对多药耐药ABA的监测与控制，有效预防和控制ABA医院感染。Abstract: Objective: To approach the antimicrobial resistance of Acinetobacter baumanii (ABA) causing nosocomial infection in brain surgery to provide the evidence for clinical control.Method: Referring to National Guide to Clinical Laboratory Operation Procedures,202 ABA strains were cultured and identified by the routine methods. The susceptibility test was performed by K-B methods recommended by CLSI. The testing results were assessed according to CLSI 2009-2011 breakpoints.Result: Specimen of respiratory tract got the highest detection rate of 68.3%.The susceptibility results showed ABA had been resistant severely to clinical commonly used antibiotics. The detection rate of imipenem-resistant ABA was 27.2%.The isolating rate of pan-resistant strains was 15.8%.Conclusion: The clinician should attach importance to etiological detection and strengthen monitoring and controlling of multidrug resistant ABA to prevent and control nosocomial infections caused by ABA.
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